Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report
Abstract
We present a case of atypical recurrent optic neuritis.
A man in his 50s presented with right optic neuritis and profound visual loss, associated with elevated inflammatory markers.
Lymph-node biopsy was consistent with sarcoidosis.
Aquaporin-4 antibodies were also present.
Three months following corticosteroid treatment, his right optic neuritis relapsed, again with raised inflammatory markers.
He was started on azathioprine and prednisolone with good effect.
A dual diagnosis of sarcoidosis and neuromyelitis optica with aquaporin-4 antibodies is very rare.
Long-term immunosuppression is required.
The case highlights the importance of identifying the features and cause of atypical optic neuritis.
Citations
Michael A. Foster , Sara Collorone , Jacqueline Palace , James Acheson & Ahmed T. Toosy. Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report. nnals of Clinical and Translational Neurology. June 2021
Sponsorship: Supported by the NIHR
Page last reviewed: 12 June, 2025
Metadata
Author(s): External author(s) only
Collection: 123456789/888
Subject(s): Eye Diseases
Format(s): Article
Date issued: 2021-06
ID: 871